Banded prolonged release active agent dosage form

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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Details

424463, 424464, 424467, 424468, 424474, 424484, 424486, 424488, A61K 924, A61K 948

Patent

active

060200006

ABSTRACT:
The present invention is directed to an active agent dosage form that is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has an insoluble material circumscribing a portion of the surface of the matrix. The invention is also directed to a method of making the active agent dosage form.

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patent: 5738874 (1998-04-01), Conte et al.
patent: 5780057 (1998-07-01), Conte et al.
Robert Langer et al., "Polymers for the Controlled Release of Macromolecules: Kinetics, Applications and External Control," AIChE Symposium Series, No. 206, vol. 77, 1981, pp. 10-20.
Dean S.T. Hsieh et al., "Zero-Order Controlled-Release Polymer Matrices for Micro- and Macromolecules," Journal of Pharmaceutical Sciences, vol. 72, No. 1, Jan. 1983, pp. 17-22.
Robert H. Zimmer, M.D., Ph.D., "How to Develop Drug Products Using the Geomatrix Technology," JAGO Pharma AG, Apr. 1997.

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