Baculovirus produced Plasmodium falciparum vaccine

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S265100

Reexamination Certificate

active

10925385

ABSTRACT:
Compositions and methods are provided for the induction of a protective immunize response in primates against a lethal challenge ofPlasmodium.

REFERENCES:
patent: 4745051 (1988-05-01), Smith et al.
patent: 5179023 (1993-01-01), Calhoun et al.
patent: 5474914 (1995-12-01), Spaete
patent: 6270800 (2001-08-01), Speaker et al.
patent: 6420523 (2002-07-01), Chang et al.
patent: 6855316 (2005-02-01), Chang et al.
patent: 2002/0058787 (2002-05-01), Strominger et al.
patent: 0154454 (1985-09-01), None
patent: 0 329 257 (1989-08-01), None
Holder et al (Nature vol. 317 pp. 270-273, Sep. 1985).
Bowie, et al., “Deciphering the message in protein sequences: tolerance to amino acid substitutions,”Science, 247, pp. 1306-1031 (1990).
Burghaus, et al., “Immunization ofAotus nancymaiwith Recombinant C Terminus ofPlasmodium falciparumMerozoite Surface Protein 1 in Liposomes and Alum Adjuvant Does Not Induce Protection against a Challenge Infection,”Infect.&Immun.64(9):3614-9 (1996).
Chang, et al., “Plasmodium falciparum: Gene Structure and Hydropathy Profile of the Major Merozoite Surface Antigen (gp195) of the Uganda-Palo Alto Isolate”Experimental Parasitology, 67: 1-11 (1988).
Chang, SP et al., “Generalized immunological recognition of the major merozoite surface antigen (gp195) ofPlasmodium falciparum,” Proc. Natl. Acad. Sci. USA 86:6343-7 (1989).
Change, SP et al., “A Carboxyl-Terminal Fragment ofPlasmodium falciparum gp195 Expressed by the Recombinant Baculovirus Induces Antibodies that Completely inhibit Parasite Growth,”J. Immunol.149(2):548-555 (1992).
Cheung et al. “Immunization with synthetic peptides of aPlasmodium falciparumsurface antigen induces antimerozoite antibodies,”Proc. Natl. Acad. Sci.USA 83:8328 (1986).
Ellis, R.W., “New Technologies for Making Vaccines,” in Vaccines, Plotkin, S.A. and Mortimer, Jr. E.A., eds., W.B. Saunders Co., Philadelphia (1988), Ch. 29, pp. 568-575.
Hall et al. “Major surface antigen gene of a human malaria parasite cloned and expressed in bacteria,”Nature, 311:379 (1984).
Herrera et al. “Conserved Polypeptides ofPlasmodium falciparumas Malaria Vaccine Candidates?”, Acta Leidensia, 60(1):107-110 (1991).
Herrera et al. “Immunization of Aotus monkeys withPlasmodium falciparumblood-stage recombinant proteins,”Proc. Natl. Acad. Sci.USA 87:4017 (1990).
Holder et al., “A hybrid gene to express protein epitopes from both sporozoite and merozoite surface antigens ofPlasmodium falciparum,” Parasitology, 97:373-382 (1988).
Holder et al., “Immunization againstPlasmodium falciparumwith recombinant polypeptides produced inEscherichia coli,” Parastic Immunology, 10:607-617 (1988).
Holder et al., “Primary Structure of the Precursor to the three major surface antigens ofPlasmodium falciparummerozoite,”Nature, 317:270-273 (1985).
Holder et al., “Processing of the precursor to the major merozoite surface antigens ofPlasmodium falciparum.” Parasitology, 94:199-208 (1987).
Holder et at. “Immunization against blood-stage rodent malaria using purified parasite antigens,”Nature, 294:361 (1981).
Holder, A.A. et al., “Immunization againstPlasmodium falciparumwith recombinant polypeptides produced inEscherichia coli,” Parasite Immunology, 10(6):607-617 (1988).
Hui et al. “Serum from Pf195 protected Aotus Monkeys InhibitPlasmodium falciparumgrowth in Vitro,”Exp. Parasitol.64:519 (1987).
Hui, et al. “Induction of Antibodies to thePlasmodium falciparumMerozoite Surface Protein-1 (MSP1) by Cross-Priming with Heterologous MSP”J. of Immunology, 153: 1195-1201 (1994).
Hui, et al., “Roles of Conserved and Allelic Regions of the Major Merozoite Surface Protein (gp195) in Immunity againstPlasmodium falciparum” Infection and Immunity, 60:1422-1433 (1992).
Knapp, 6. et al. “A histidin alanine rich recombinant antigen protects aotus monkeys fromP. falcipariuminfection,”Behrina Inst. Mitt.82:349-59 (1988).
Kumar. S. et al.. “Immunogenicity and Efficacy inAotusMonkeys of Four RecombinantPlasmodium falciparumVaccines in Multiple Adjuvant Formulations Based on the 19-Kilodalton C Terminus of Merozoite Surface Protein 1 ,”Infect.&Immun. 68(4):2215-2223 (2000).
Lew et al. “A protective monoclonal antibody recognizes a linear epitope in the precursor to the major merozoite antigens ofPlasmodium chabaudi adami,”Proc. Natl. Acad. Sci. USA 86:3768 (1989).
Locher, CP et at., “Plasmodium falciparum: gp195 Tripeptide Repeat-Specific Monoclonal Antibody Inhibits Parasite Growth in Vitro”Exp. Parisitol., 84:74-83 (1996).
Majarian et al. “Passive Immunization against Murine Malaria with an IgG3 Monoclonal Antibody,”J. Immunol.132:3131 (1984).
Murphy, V.F. et al., “Expression of hybrid malaria antigens in insect cells and their engineering for correct folding and secretion.”Parasitology, 100 pt. 2:177-183 (1990).
Nishimura, T.A.T., “Distribution of MSP-1 Dimorphism in Papua New Guinea and the Importance of BVp42 Dimorphism in Antibody Recognition”, Master of Science in MicrobiologyThesis, University of Hawaii (Dec. 1999).
Odink K.G. et al., “Expression of cloned cDNA for a major surface antigen ofPlasmodium falciparummerozoite,”FEBS Lett., (1984) 108-12.
Patarroyo et al. “A synthetic vaccine protects humans against challenge with asexual blood stages ofPlasmodium falciparummalaria.”Nature, 332:158 (1988).
Patarroyo et al. “Induction of protective immunity against experimental infection with malaria using synthetic peptides,”Nature, 328:629 (1987).
Patarroyo et al. “Protective Synthetic Peptides against ExperimentalPlasmodium falciparum-induced Malaria,”Vaccines 87 (Brown, Chanock, Lerner. ed.) Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY. 117-124(1987).
Perlaza et al., “Immunogenicity of fourPlasmodium falciparumpreerythrocytic antigens in Aotus lemurinus monkeys,”Infection and Immunity, 66(7):3423-3438 (1998).
Perrin et al. “Antimalarial immunity in Saimiri monkeys. Immunization with surface components of asexual blood stages.,”J. Exp. Med. 160:441-451 (1984).
Rodriguez et al. “Studies In Owl Monkeys Leading to the Development of a Synthetic Vaccine Against the Asexual Blood Stages ofPlasmodium falciparum,” Am. J. Trop. Med. Hyg.43:339 (1990).
Ruebush et al.. “Immunization of Owl Monkeys with a Combination ofPlasmodium falciparumAsexual Blood-Stage Synthetic Peptide Antigens,”Am. J. Trop. Med. Hyg.43:355-366 (1990).
Saul et al., Second African Malaria Vaccine Testing Network Meeting, Accra, Ghana, Nov. 24-26, 1997.
Schreiber, et al., “A eukaryotic expression vector for the study of nuclear localization signals,”Gene, 150(2):411-412 (Dec. 1994).
Schwarz et al, “Structural Diversity of the Major Surface Antigen ofPlasmodium falciparumMerozoites,”Mol. Cell. Biol., 6(3):964-968 (1986).
Siddiqui et al. “Merozoite surface coat precursor protein completely protects Aotus monkeys againstPlasmodium falciparummalaria,” 1987.Proc. Natl. Acad. Sci.USA 84:3014.
Smilek, D. et al., “A single amino acid change in myelin basic protein peptide confers the capacity to prevent rather than induce EAE”,Proc. Natl. Acad. Sci.USA 88:9633-37 (1991).
Soltysik, “Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid rules in adjuvant function,”Vaccine1995, 13(15):1403-1410.
Stowers, AW et al., “A recombinant vaccine expressed in the milk of transgenic mice protects Aotus monkeys from a lethal challenge withPlasmodium falciparum,” 99(1):339-344 (2002).
Stowers, AW et al., “Efficacy of Two Alternate Vaccines Based onPlasmodium falciparumMerozoite Surface Protein 1 in anAotusChallenge Trial,” Infect. &

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Baculovirus produced Plasmodium falciparum vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Baculovirus produced Plasmodium falciparum vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Baculovirus produced Plasmodium falciparum vaccine will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3867000

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.