Baculovirus insect control compositions with enhanced lethality

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Virus or bacteriophage

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424 932, A01N 6300

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active

059852690

ABSTRACT:
A method of enhancing baculovirus disease in pests on a crop is provided through an insect control composition by applying an insect control composition to the crop. The applied composition includes a baculovirus that is infectious for at least one pest feeding on the crop and an enhancing agent for the baculovirus. The enhancing agent is preferably administered so as to be ingestible by the pest together with the baculovirus. A preferred enhancing agent is mannitol which increases the mortality of larval tobacco budworms feeding on cotton when infected with Autographa californica by 238%.

REFERENCES:
Hoover et al., "Influence of Induced Plant Defenses in Cotton and Tomato on the Efficacy of Baculoviruses on Noctuid Larvae," J. Chem. Ecol., 24(2), pp. 253-271 (1998).
Hoover et al., "Effects of Plant Identity and Chemical Constituents on the Efficacy of a Baculoviruses Against Heliothis virescens," J. Chem. Ecol., 24(2), pp. 221-252 (1998).
Ignoffo and Garcia, "Antioxidant and Oxidative Enzyme Effects on the Inactivation of Inclusion Bodies of the Heliothis Baculovirus by Simulated Sunlight-UV," Environ. Entomol., 23(4), pp. 1025-1029 (1994).
Halliwell et al., "The Deoxyribose Method: A Simple `Test-Tube` Assay for Determination of Rate Constants for Reactions of Hydroxyl Radicals," Anal. Biochem., 165, pp. 215-219 (1987).
Halliwell et al., "Methods for the Measurement of Hydroxyl Radicals in Biochemical Systems: Deoxyribose Degradation and Aromatic Hydroxylation," Methods of Biochemical Analysis, 33, pp. 59-90.
Wu et al., "Propyl Gallate as a Hepatoprotector in vitro and in vivo," Biochem. Pharm., 48(2), pp. 419-422 (1994), abstract only.

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