Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1998-08-20
2000-07-18
Guzo, David
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4353201, 4352351, 435348, 435325, 435236, 435455, 435456, 435 914, 435 9142, 435 9141, 536 231, 536 2372, C12P 2100, C12N 1586, C12N 510, C07H 2104
Patent
active
060905840
ABSTRACT:
An baculovirus artificial chromosome is disclosed which has the lef-8 gene inactivated. The baculovirus artificial chromosome allows the cloning and expression of heterologous genes in insect and mammalian cells without killing the host cells. Also disclosed is an infectious baculovirus comprising the artificial chromosome and a cell containing the chromosome. Also disclosed is an insect cell which expresses the LEF-8 gene in the absence of a baculovirus chromosome. Also disclosed is a method to express heterologous proteins in eukaryotic cells using the baculovirus artificial chromosome.
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Farrell Patrick J.
Hashimoto Yoshifumi
Iatrou Kostas
Guzo David
University Technologies International Inc.
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