Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant virus encoding one or more heterologous proteins...
Reexamination Certificate
2011-03-22
2011-03-22
Mosher, Mary E (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant virus encoding one or more heterologous proteins...
C424S193100, C424S194100, C424S196110, C424S202100, C424S204100, C424S226100, C424S227100, C530S806000, C530S810000
Reexamination Certificate
active
07910110
ABSTRACT:
The present invention relates to vaccines comprising a bacteriophage which has been engineered to express an immunogenic protein/peptide and wherein the surface of the bacteriophage has not been modified to contain proteins/peptides designed to target the phage to receptors on the surface of specific cell types.
REFERENCES:
patent: 5736388 (1998-04-01), Chada et al.
patent: 6054312 (2000-04-01), Larocca et al.
patent: 7407790 (2008-08-01), Hone
patent: 2003/0113293 (2003-06-01), Bermudes et al.
patent: 0 181 117 (1986-05-01), None
patent: WO 96/21007 (1996-07-01), None
patent: WO 98/05344 (1998-02-01), None
patent: WO 98/37916 (1998-09-01), None
patent: WO 98/39031 (1998-09-01), None
patent: WO 98/56423 (1998-12-01), None
patent: WO 99/10014 (1999-03-01), None
patent: WO 99/55720 (1999-11-01), None
patent: WO 00/67761 (2000-11-01), None
patent: WO 02/076498 (2002-10-01), None
Pugh, et al. Expression of the X Gene of Hepatitis B Virus. Journal of Medical Virology. 1986; vol. 20 Issue 3, pp. 229-246.
Gough, NM. Core and E antigen synthesis in rodent cells transformed with hepatitis B virus DNA is associated with greater than genome length viral messenger RNAs. J Mol Biol. Apr. 25, 1983;165(4):683-99.
Stoller-Keller, et al. Development of hepatitis C virus vaccines: challenges and progress. Expert Rev Vaccines. Mar. 2009; 8(3):333-45 (abstract only cited).
Aggarwal and Jameel, Hepatitis E vaccine. Hepatol Int. Sep. 2008; 2(3): 308-315.
Aujame et al. “Experimental Design Optimization of Filamentous Phage Transfection into Mammalian Cells by Cationic Lipids”,Biotechniques28:1202-1213 (2000).
Bastien et al. “protective Immune Responses Induced by the Immunization of Mice with a Recombinant Bacteriophage Displaying a Epitope of the Human Respiratory Syncytial Virus”Virology234: 118-122 (1997).
De Berardinis et al. “Phage Display of Peptide Epitopes from HIV-1 Elicits Strong Cytolytic Response”Nature Biotechnology18:2000.
Gaubin et al. “Processing of Filamentous Bacteriphage Virions in Antigen-Presenting Cells Targets Both HLA Class I and Class II Petptide Loading Compartments”DNA and Cell Biology22(1): 11-18 (2003).
Horst et al. “Gene Transfer to Human Cells: Transducing Phage λplacGene Expression in GMl-gangliosidosis fibroblasts”PNAS72(9): 3531-3535 (1975).
International Search Report Corresponding to PCT/GB02/01413 mailed Jun. 13, 2003.
Ishiura et al. “Phage Particle-Mediated Gene Transfer to Cultured Mammalian Cells”Molecular and cellular Biology2(6): 607-616 (1982).
Monahan et al. “Viral Vectors for Gene Transfer into Antigen Presenting Cells”Current Opinion in Molecular Therapeutics1(5): 558-564 (1999).
Okayama et al. “Bacteriophage Lambda Vector for Transducing a cDNA Clone Library into Mammalian Cells”,Molecular and Cellular Biology5:1136-1142 (1985).
Srivatsan et al. “Plasmid, phage, and genomic DNA-mediated transfer and expression of prokaryotic and eukaryotic genes in cultured human cells”,Cytogenet Cell Genet38:227-234 (1984).
Vincent et al. “An In Vitro, Complement-Dependent Model of Particle Transfer from Erythrocytes to Macrophages”Immunopharmacology49(1-2): 90 (2000).
Douglas, R.G. “The Jeremiah Metzger Lecture, Vaccine Prophylaxis Today: Its Science, Application and Politics”Transactions of the American Clinical and Climatological Associationvol. 109, p. 185-198 (1998).
Ishiura et al. “Stability of the Transformants Obtained by Phage Particle-Mediated Gene Transfer”Cell Structure and Function14:495-499 (1989).
Koide et al. “DNA Vaccines”Jpn J Pharmacol83:167-174 (2000).
Clark Jason
March John Bernard
BigDNA Limited
Mosher Mary E
Myers Bigel Sibley & Sajovec P.A.
Snyder Stuart W
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