Bacteriophage-containing therapeutic agents

Details Bacteriophage-containing therapeutic agents Bacteriophage-containing therapeutic agents

2004-07-23

2010-10-05

Mondesi, Robert B (Department: 1645)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Virus or bacteriophage

C424S184100, C424S170100, C424S260100, C424S093470

Reexamination Certificate

active

07807149

ABSTRACT:
The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting ofP. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity againstP. aeruginosaand combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates ofP. aeruginosafrom canine ear infections.

REFERENCES:
patent: 4828999 (1989-05-01), Jackson
patent: 6461608 (2002-10-01), Averback et al.
patent: 2002/0001590 (2002-01-01), Kelly et al.
patent: 2002/0090356 (2002-07-01), Waddell et al.
patent: WO-97/39111 (1997-10-01), None
patent: WO-98/47521 (1998-10-01), None
patent: WO-01/50866 (2001-07-01), None
patent: WO-02/07742 (2002-01-01), None
patent: WO-2004/062677 (2004-07-01), None
Slopek et al. (Archivum Immunologiae Et Therapiae Experimentals, 1984; 32(3): 317-35).
Carlton, Archivum Immunologiae Et Therapiae Experimentalis (1999) 47(5):267-274.
Database WPI Accession No. 1990-021061, Class B04 and SU 1 472 500, Apr. 15, 1989.
Database WPI Accession No. 2002-689103, and RU 2186574, Jan. 24, 2001.
Hanlon et al., Applied and Environmental Microbiology (2001) 67(6):2746-2753.
International Search Report for PCT/GB2004/003237, mailed on Nov. 8, 2004, 6 pages.
Kudva et al., Appl. Environ. Biol. (1999) 65:3767-3773.
Soothill, Burns (1994) 20(3):209-211.
Tait et al., Biofouling (2002) 18(4):305-311.
UK Search Report for GB 0317240.0 dated Oct. 15, 2003.

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