Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-05-26
1989-08-29
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 21, 514885, 424405, 424 92, 530350, 530825, A01N 2500, A61K 3702, C07G 702
Patent
active
048617547
ABSTRACT:
It has been found that bacteriocins are able to kill virally-infected mammalian cells, including virally infected white blood cells. Accordingly, viral infections can be detected and ultimately treated using the bacteriocins and the methods described herein. The invention is particularly suited to detection and treatment of AIDS infection and infectious mononucleosis infection.
REFERENCES:
Saito et al., Chemical Abstracts, vol. 91, No. 84180y (1979).
Saito et al., "Effects of a Bacteriocin from Mycobacterium Smegmatis on BALB/3T3 and Simian Virus 40 Transformed BALB c Mouse Cells" Microbiol. Immunol., vol. 25 (1), 13-22, Jan./1981.
Saito et al., "Effect of a Bacteriocin Produced by Mycobacterium Smegmatis on Growth of Cultured Tumor and Normal Cells" Cancer Research 39, 5114-5117, Dec./1979.
Watanabe et al., "Cytotoxicity of Pyocin 52 to Tumor and Normal Cells and its Interaction with Cell Surfaces" Biochim. et Biophysica Acta 633 (1980) 77-86.
Sypula et al., "Effect of Bacteriocins on Interferon Production" Arch. Immun. Ther. Exp., 25, 651-653, 1977.
Musclow et al., "Bacteriocin and Flow Cytometry in Laboratory Diagnosis of Leukemic Peripheral Blood Lymphocytes and Bone Marrow Cells" Eur. J. Cancer Clin. on Col., vol. 19, No. 2, pp. 163-171, 1983.
Farkas-Himsley, "Bacteriocins as Growth Inhibitors of Neoplastic and Tumorigenic Cells" IRCS Journal of Medical Science, vol. 4, pp. 291-295, Jul. 1976.
Kight John
Nutter Nathan M.
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