Bacterin for the treatment of necrophorum diseases and a method

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Bacteria or actinomycetales

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435243, 435245, 4352521, A01N 6300

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active

061327093

ABSTRACT:
A method for treating cattle and sheep to prevent foot rot and/or liver necrosis comprising administering a Fusobacterium necrophorum bacterin which is a .beta.-propriolactone inactivated Fusobacterium necrophorum isolate to the animal being treated.

REFERENCES:
patent: 4061751 (1977-12-01), Adam
patent: 4203968 (1980-05-01), Harris et al.
Garcia et al, "Biological Characterization of Fusobacterium necrophorum Cell Fractions in Preparation for Toxin and Immunization Studies", Infection and Immunity, Apr., 1975, pp. 609-616.
Abe et al, "Immunization of Mice Against Fusobacterium necrophorum Infection by Parenteral or Oral Administration of Vaccine", Am. J. Vet. Res., vol. 39, No. 1, pp. 115-118, Jan., 1978.
Synthea Mass, The Immune Responses of Mice and Cattle to Fusobacterium necrophorum, Aug. 1986.
John William Evans, Jr., Serological Investigations of Fusobacterium necrophorum, (Dec. 1983).
Biosis Previews Database Biosis, Phila., PA., Clark, B.L. et al, "Studies into Immunization of Cattle Against Interdigital Necrobacillosis", Abstract Nb: 82053868 and Aust. Vet. J., vol. 63 No. 4, 1986 pp. 107-110.
Kaititch, "Etude Comparative Sur La Valeur Prophylactique de 2 Vaccins Contre Le Pietin Du Mouton", Bul. Soc. Vet. et Med. Comparee, vol. 76, No. 4 (Lyon 1974).
Am. J. Vet. Res. (1983), 44(9), 1789-92 Coden; Ajvrah; Issn; 0002-9645, Sep., 1983, C.M. Scanlan et al, Comparative biological features of a rat liver abscess model induced with three Fusobacterium necrophorumstrains.

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