Bactericidal/permeability-increasing protein (BPI) deletion anal

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 435325, 435358, 536 232, C12P 2106, C12N 1500, C12N 500, C12N 506, C07H 2104

Type

Patent

Status

active

Patent number

060871261

Description

ABSTRACT:
Novel BPI deletion analogs are provided that consist of amino acid residues 10 through 193 of mature human BPI wherein the cysteine residue at BPI amino acid position 132 is replaced by another amino acid. Fusion proteins comprising these analogs are also provided, as are polynucleotides encoding these products, materials and methods for their recombinant production, compositions and medicaments of these products, and therapeutic uses for these products.

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