Bactericidal/permeability-increasing protein (BPI) deletion anal

Details Bactericidal/permeability-increasing protein (BPI) deletion anal Bactericidal/permeability-increasing protein (BPI) deletion anal

1999-06-18

2000-07-11

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 435358, 536 232, C12P 2106, C12N 1500, C12N 500, C12N 506, C07H 2104

Patent

active

060871261

ABSTRACT:
Novel BPI deletion analogs are provided that consist of amino acid residues 10 through 193 of mature human BPI wherein the cysteine residue at BPI amino acid position 132 is replaced by another amino acid. Fusion proteins comprising these analogs are also provided, as are polynucleotides encoding these products, materials and methods for their recombinant production, compositions and medicaments of these products, and therapeutic uses for these products.

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