Drug – bio-affecting and body treating compositions – Dentifrices – Ferment containing
Patent
1983-02-07
1984-10-09
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Dentifrices
Ferment containing
424 53, 424 94, 424130, 424230, 424258, 424274, 424317, 424319, 424330, 424338, 435 78, 435264, A61K 728, A61K 720, A61K 3748, A61K 3340
Patent
active
044761082
ABSTRACT:
The bactericidal method of the invention comprises forming a bactericide having a limited period of bacteriological activity with the bactericide including; a peroxide, a peroxidase and a source of donor molecules adapted to act as a substrate for said peroxidase; activating the bactericide to cause a catalyzed reaction by said peroxidase for generating free radicals from said source of donor molecules and simultaneously applying the bactericide for killing bacteria in the treatment of dental disease in situ such as in the oral cavity or as a denture cleaner.
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Elliott, K. A. C.: Oxidations Catalysed by Horseradish & Milk Peroxidases, Biochem. J. 26: 1281-1290, (1932).
Sizer, I. W. The Oxidative Inactivation of Poison Ivy Allergens by Peroxidase: J. of Invest. Dermatology 16, 103-110, (1951).
J. Clinical Periodon. 6, 115-130, (1979), Wennstrom et al.
Kessler Jack H.
Rosenbaum Robert S.
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