Bacterial superantigen vaccines

Details Bacterial superantigen vaccines Bacterial superantigen vaccines

2008-05-27

2008-05-27

Allen, Marianne P (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S069100, C435S071100, C435S071300, C435S320100, C435S325000, C435S252300, C435S252330, C536S023100, C536S023700

Reexamination Certificate

active

07378257

ABSTRACT:
The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described.

REFERENCES:
patent: WO 96/36366 (1996-11-01), None
patent: WO 97/36932 (1997-10-01), None
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