Bacterial cell surface protein with fibronectin, fibrinogen, col

Details Bacterial cell surface protein with fibronectin, fibrinogen, col Bacterial cell surface protein with fibronectin, fibrinogen, col

1993-09-10

1999-11-09

Duffy, Patricia A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424823, 514 2, 530350, A61K 39085

Patent

active

059809086

ABSTRACT:
The invention is concerned with a vaccine composition comprising an effective amount of an isolated protein derived from Staphylococcal aureus having the ability to bind fibronectin. The protein has a molecular weight of 165,000 daltons and optionally also contains a protein having a molecular weight of 87,000 daltons. The protein has the ability to elicit antibody production and a level of protein to elicit antibody production. The level of protein is sufficient to produce protection upon challenge with a Staphylococcus aureus bacterial strain in a mammal, particularly a ruminant, by forming antibodies against the Staphylococcus aureus bacterial strain.

REFERENCES:
patent: 3917818 (1975-11-01), Botes
patent: 4197290 (1980-04-01), Yoshida
patent: 4312942 (1982-01-01), Blobel et al.
patent: 4327082 (1982-04-01), Armitage
patent: 4425330 (1984-01-01), Norcross et al.
patent: 4444343 (1984-04-01), Buchannan et al.
patent: 4645757 (1987-02-01), Hjerten et al.
patent: 4784989 (1988-11-01), Hook et al.
patent: 4795803 (1989-01-01), Lindberg et al.
patent: 5320951 (1994-06-01), Hook et al.
Abrahmsen et al.--Nucl. Acid Res. 14(18):7487-7500 (1986).
Chhatwal et al.--Comp. Immunol. Microbiol. Infect. Dis. 10(2):99-108 Abstract (1987).
Duggleby et al.--Nuc. Acid. Res. 11(10):3065-3076 (1983).
Espersen et al.--Infect. and Immun. 37(2):526-531 (Aug. 1982).
Flock et al.--EMBO J. 6(8):2351-2357 (1987).
Froman et al.--J. Biol. Chem. 262(14):6564-6571 (1987).
Keil-Dlouha et al.--Biochem. Biophys. Acta. 727:115-21 (1983).
Lofdahl et al.--Proc. Natl. Acad. Sci. 80:697-701 (Feb. 1983).
Mamo et al.--Micro. Pathog. 2(6):417-424 Abstract (1987).
McGavin et al.--J. Biol. Chem. 266(13):8343-7 (1991).
Myhre--J. Med. Microbiol. 18(2):189-196 Abstract (1984).
Myhre et al.--Infect. Immun. 40(1):29-34 (1983).
Nuesch et al.--Gene 32:243-249 (1984).
Overbeeke et al.--J. Mol. Biol. 163:513-532 (1983).
Raja et al.--Infect. Immun. 58(8):2593-8 (1990).
Ryden et al.--J. Biol. Chem. 258(5):3396-3401 (Mar. 1983).
Sambrook et al.--Molecular Cloning: A Laboratory Manuel, (2d), 6.39-6.43, B.9 (1989).
Signas et al.--Proc. Natl. Acad. Sci. 86:699-703 (1989).
Switalski et al.--Eur. J. Clin. Microbiol. 1:381-387 (1982).
Beachey et al. J. of Infect. Dis 143(3):325-345. 1981.
Funderberg et al. (Ed) "Basic and Clinical Immunology" Published by Lange Medical Publications (CA) 1980 see p. 606.
R.M. Chanock et al. (ed.), "Vaccines 95, Molecular Approaches to the Control of Infectious Diseases", published by Cold Spring Harbor Laboratory Press, see pp. 249-255, 1995.

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