Bacterial cell extract, process for preparing same, antitumor pr

Details Bacterial cell extract, process for preparing same, antitumor pr Bacterial cell extract, process for preparing same, antitumor pr

1981-06-08

1988-02-23

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

4241951, A61K 3902, A61K 3578

Patent

active

047269472

ABSTRACT:
Cells of a microorganism, such as Mycobacterium tuberculosis, belonging to the genus Mycobacterium are disrupted in distilled water or a suitable buffer solution, and then centrifuged or filtrated to remove the cell wall residue. To the aqueous cell-free extract is added a polyvalent metal salt or an antibiotic, such as streptomycin sulfate, which acts as a flocculant to form a precipitate. The precipitate consists essentially of sugar, protein, lipid, and nucleic acid. Owing to its high antitumor and adjuvant activities as well as its slight side effects, it can be used as antitumor and adjuvant preparations.

REFERENCES:
patent: 3399263 (1968-08-01), Strazdins et al.
patent: 3600378 (1971-08-01), Marsh et al.
patent: 3790665 (1974-02-01), Glass et al.
patent: 3956481 (1976-05-01), Jolles et al.
patent: 3976544 (1976-08-01), Adam et al.
patent: 4001395 (1977-01-01), Jolles et al.
Lamensans et al., Proc. Nat. Acad. Sci., 72, pp. 3656-3660 (1975).
Azuma et al., J. of Nat. Cancer Inst., 52, pp. 95-100 (1974).
Adam et al., Proc. Nat. Acad. Sci., 69, pp. 851-854 (1972).
Weiss, Medical Clinics of N.A., vol. 60, No. 3, pp. 473-497 (1976).
Youmans et al, J. of Bacteriology, 99, pp. 42-50 (1969).

Affiliated with

Also associated with

Rating

Bacterial cell extract, process for preparing same, antitumor pr does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Bacterial cell extract, process for preparing same, antitumor pr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bacterial cell extract, process for preparing same, antitumor pr will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-602072