Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1987-12-31
1991-03-12
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435142, 435146, 435170, 4352521, 43525234, 4352533, 4352536, C12R 138, C12P 744, C12N 1500
Patent
active
049992929
ABSTRACT:
Bacteria that metabolize phenylacetate along a mandelate-to-cis,cis-muconate pathway are disclosed. Bacteria that express the pathway for metabolizing phenylacetate through a mandelate intermediate can be isolated reproducibly by first selecting bacteria that can utilize both L-phenylalanine and mandelate as the sole carbon source and then blocking alternate pathways for the degradation of L-phenylalanine. The activity of selected enzymes along the mandelate-to-cis,cis-muconate pathway can be blocked in these bacteria to effect the accumulation of selected intermediates.
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Derwent Abs. 87-109917/16 Hummel et al. (EP 218863) (Apr. 22, 1987).
Anderson David M.
Geusz Steven D.
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