Backbone-substituted bifunctional DOTA ligands, complexes...

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C534S016000, C540S465000, C540S474000, C540S473000

Reexamination Certificate

active

10525673

ABSTRACT:
Backbone-substituted 1,4,7,10-tetraaza cyclododecane-N,N′,N″,N′″-tetraacetic acid compounds, metal complexes thereof, compositions thereof, conjugates thereof, and methods of use in diagnostic imaging and treatment of a cellular disorder.

REFERENCES:
patent: 4923985 (1990-05-01), Gansow et al.
patent: 5049667 (1991-09-01), Schaefer et al.
patent: 5334371 (1994-08-01), Gries et al.
patent: 5358704 (1994-10-01), Desreux et al.
patent: 5428154 (1995-06-01), Gansow et al.
patent: 5428156 (1995-06-01), Mease et al.
patent: 5434287 (1995-07-01), Gansow et al.
patent: WO 89/11475 (1989-11-01), None
patent: WO 95/19347 (1995-07-01), None
patent: WO 95/31444 (1995-11-01), None
patent: WO 96/14339 (1996-05-01), None
patent: WO 02/062398 (2002-08-01), None
patent: WO 03/101919 (2003-12-01), None
Moi et. al.; 1988; J. Am. Chem. Soc. 110, 6266-6267.
Benter, Yinon; Gadolinium; www.chemicalelements.com/elements/gd.html.
Atsarkin et al.,J. Phys. Chem. A., 105(41), 9323-9327 (2001).
Cox et al.,J. Chem. Soc. Perkin Trans., 1, 2567-2576 (1990).
Forsberg et al.,Inorg. Chem., 34(14), 3705-3715 (1995).
Hnatowich et al.,Science, 220, 613-615 (1983).
Howard et al.,Chem. Commun., 1381-1382 (1998).
Jacques et al.,J. Alloys Compd., 249, 173-177 (1997).
Kasprzyk et al.,Inorg. Chem., 21(9), 3349-3352 (1982).
Keire et al.,Inorg. Chem., 40(17), 4310-4318 (2001).
Kline et al.,Bioconjugate Chem., 2(1), 26-31 (1991).
Kodama et al.,Inorg. Chem., 30(6), 1270-1273 (1991).
Krejcarek et al.,Biochem. Biophys. Res. Commun., 77(2), 581-585 (1977).
Lewis et al.,Bioconjugate Chem., 5(6), 565-576 (1994).
Lewis et al.,Bioconjugate Chem., 12(2), 320-324 (2001).
McCall et al.,Bioconjugate Chem., 1(3), 222-226 (1990).
McMurray et al.,Bioconjugate Chem., 3(2), 108-117 (1992).
Milenic et al.,Nuclear Medicine and Biology, 29, 431-442 (2002).
Mirzadeh et al.,Bioconjugate Chem., 1(1), 59-65 (1990).
Peterson et al.,Bioconjugate Chem., 10(2), 316-320 (1999).
Ruegg et al.,Cancer Res., 50, 4221-4226 (1990).
Runge et al.,Invest. Radiol., 30(2), 123-130 (1995).
Siaugue et al,Tetrahedron Letters, 41, 7443-7446 (2000).
Szilágyi et al.,Inorg. Chim. Acta., 298, 226-234 (2000).
Takenouchi et al.,J. Org. Chem., 58, 6895-6899 (1993).
Wu et al.,Bioorg. Med. Chem., 5(10), 1925-1934 (1997).
Bambirra et al.,Chem. Commun., 637-638 (2001).
Berreau et al.,Inorg. Chem., 37, 1091-1098 (1998).
Chong et al.,J. Med. Chem., 45(16), 3458-3464 (2002).
Curtis et al.,J. Chem. Soc. A., 1015-1018 (1966).
Fortier et al.,J. Chem. Soc. Dalton Trans., 101-109 (1991).
Kovacs et al.,Synth. Commun., 29(16), 2817-2822 (1999).
Male et al.,Inorg. Chem., 39, 5483-5491 (2000).
Pletnev,Can. J. Chem., 72, 1404-1411 (1994).
Renn et al.,Bioconjugate Chem., 3, 563-569 (1992).
Rossi et al.,Tetrahedron Letters, 39, 7159-7162 (1998).
Tei et al.,J. Chem. Soc. Dalton Trans., 2793-2799 (2000).
Warden et al.,Org. Lett., 3(18), 2855-2858 (2001).
Weisman et al.,J. Org. Chem., 61, 5186-5187 (1996).
Chappell et al.,Nuclear Medicine and Biology, 30, 581-595 (2003).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Backbone-substituted bifunctional DOTA ligands, complexes... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Backbone-substituted bifunctional DOTA ligands, complexes..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Backbone-substituted bifunctional DOTA ligands, complexes... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3957924

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.