Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1992-10-19
1994-04-12
Wax, Robert A.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
9352525, A01N 6300
Patent
active
053023870
ABSTRACT:
The subject invention concerns a novel microbe and genes encoding novel toxin proteins with activity against cockroaches. Cockroaches are common house pests, and they create problems in hospitals, the food industry and in agriculture. The novel Bacillus thuringiensis microbe of the invention is referred to as B.t. PS185L8. The subject invention also concerns the use of PS201T6 to control cockroaches. The spores or crystals of these microbes, or variants thereof, are useful to control cockroaches in various environments. The genes of the invention can be used to transform various hosts wherein the novel toxic proteins can be expressed.
REFERENCES:
patent: 4966765 (1992-10-01), Payne et al.
Singh, Gur Jai Pal, and Sarjeet S. Gill (1985) "Myotoxic and Neurotoxic Activity of Bacillus thuringiensis var. israelensis Crystal Toxin" Pesticide Biochemistry and Physiology 24:406-414.
Ulewicz, K. (1976) "Studies on the infection of the cockroaches (Blattella germanica [L] with B. thuringiensis" Biological Abstracts 61(2):858 abstract no. 8274.
Penev, I. (1981) "Study of some methods and agents for control of synanthropic cockroaches" Chemical Abstracts 94(13):262 abstract no. 97934j.
Krieg, Von A., A. M. Huger, G. A. Langenbruch, and W. Schnetter (1983) "Bacillus thuringiensis var. tenebrionis: ein neuer, gegenuber Larven von Coleopteren wirksamer Pathotyp" Z. ang. Ent. 96:500-508.
Couch, Terry L. (1980) "Mosquito Pathogenicity of Bacillus thuringiensis var. israelensis" Developments in Industrial Microbiology 22:61-76.
Beegle, Clayton C. (1978) "Use of Entomogenous Bacteria in Agroccosystems" Developments in Industrial Microbiology 20:97-104.
Lecadet et al. J. Invert Path vol. 49 pp. 37-48 (1987).
Hofte et al. Microbial Reviews vol. 53 No. 2 pp. 242-255 (1989).
Brower David O.
Kennedy M. Keith
Payne Jewel M.
Randall John B.
Mycogen Corporation
Schmickel D.
Wax Robert A.
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