Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1994-06-02
1996-03-19
Wax, Robert A.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
435 691, 435220, 435222, 4352523, 43525231, 536 232, 935 14, 935 29, 935 48, 935 74, C12N 954, C12N 1557, C12N 1562, C12N 1575
Patent
active
055003648
ABSTRACT:
Mutant B. lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
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Christianson Teresa
Goddette Dean
Ladin Beth F.
Lau Maria R.
Paech Christian
Chow Frank S.
Cognis, Inc.
Drach John E.
Jaeschke Wayne C.
Moore William W.
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