Bacillus containing a 5'inosinate dehydrocenase gene

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435253, 435320, 536 27, C12P 1940, C12N 120, C12N 1100, C07H 2104

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047496509

ABSTRACT:
A DNA having a 5'-inosinate dehydrogenase gene and further having a Hind III cleavage site 2.9 kilo base pairs can be produced from the chromosomal DNA of a guanosine and/or xanthosine-producing strain of the genus Bacillus. A vector with the DNA obtained above is used to transform Bacillus strain capable of producing guanosine, and the transformed Bacillus strain is useful to increase the guanosine productivity as compared with the case in which a strain before transformantion is used.

REFERENCES:
Biochemistry, Lehninger, pp. 729-735, (2d ed.).
Matsui et al, Agric. Biol. Chem., 43, 1739-1744 (1979).
Miyagawa et al, Biotechnology, 4, pp. 225-228 (1986).

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