Bacillus anthracis protective antigen

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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Reexamination Certificate



A polynucleotide sequence is provided, comprising: a nucleic acid sequence having at least 75% identity to SEQ ID NO: 1, wherein said nucleic acid sequence encodes recombinantBacillus anthracisProtective Antigen (rPA); or a fragment of said nucleic acid sequence wherein said fragment encodes a fragment of recombinantBacillus anthracisProtective Antigen (rPA).Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA or a fragment thereof.The invention further provides antigenic compositions and corresponding methods and uses for inducing an immune response.

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patent: 2004/0028695 (2004-02-01), Park
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patent: WO 02/04646 (2002-01-01), None
patent: WO 03/040179 (2003-05-01), None
patent: WO 2004/003139 (2004-01-01), None
patent: WO 2004/024067 (2004-03-01), None
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