Baccatin III derivatives

Details Baccatin III derivatives Baccatin III derivatives

1995-06-07

1996-12-03

Trinh, Ba K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549511, C07D30514

Patent

active

055809979

ABSTRACT:
New Baccatin III derivatives are disclosed for use in making taxoid compounds having formula (I) illustrated herein that exhibit antitumor activity.

REFERENCES:
patent: 5254580 (1993-10-01), Chen et al.
Gu eritte-Voegelein et al., "Relationships between the Structure of Taxol Analogues and Their Antimitotic Activity," J. Med. Chem. 1991, 34, 992-998.
Klein et al., "Synthesis of Ring B-Rearranged Taxane Analogs," J. Org. Chem. 1994, 59, 2370-2373.

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