Azulenic retinoid compounds, compositions and methods

Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

554221, 560128, 562510, 568445, 568823, 568828, C07C23100

Patent

active

052350762

ABSTRACT:
Novel azulenic retinoid compounds and therapeutic compositions are disclosed, along with method for their production and use as anti-cancer and cancer-prevention agents. The compositions of the present invention will also find use in treating dermatological disorders such as acne and psoriasis, as well as dermatologically-related conditions such as repair and effacement of wrinkles.

REFERENCES:
patent: 4310546 (1982-01-01), Gander
patent: 4565863 (1986-01-01), Ballag et al.
patent: 4568757 (1986-02-01), Carroll et al.
patent: 4727088 (1988-02-01), Scott et al.
patent: 4826871 (1989-05-01), Gressel et al.
patent: 4885311 (1989-12-01), Parish et al.
patent: 4902604 (1990-02-01), Yamaguchi et al.
patent: 4904566 (1990-02-01), Schrott et al.
patent: 4912134 (1990-03-01), Yasunami et al.
Chemical Abstracts, vol. 99, No. 11, 1983, p. 589 88414r.
Chemical Abstracts, vol. 102, p. 315, 100823p.
Chemical Abstracts, vol. 102, #12, p. 315, 100823p, 1985.
Asato et al, Journal of the American Chemical Society, vol. 112, #20, pp. 7398-7399, 1990.
Horino et al, Bulletin of the Chemical Society of Japan vol. 64, #1, 1991, pp. 183-190.
Zarilli, G. R., "synthesis of retinal analogs for biological and bioorganic studies: Chlamydomonas, a new model for photoreceptor studies," Ph.D. thesis submitted to Columbia University, 1984, pp. 48-88 and 132-142.
Liu, R. S. H. and A. E. Asato, Methods Enzymol. 88:506 (1982).
Nakanishi, et al., Pure Appl. Chem. 61:361 (1989).
Foster, et al., Biochem. 28:819 (1989).
Derguini, et al., Pure Appl. Chem. 58:719 (1986).
Derguini, et al., J. Am. Chem. Soc. 105:646 (1983).
Lugtenburg, et al., J. Am. Chem. Soc. 108:3104 (1986).
Sandorfy, C. and Vocelle, D., Can. J. Chem. 64:2251 (1986).
Mead, et al., Tetrahedron Lett. 28:259 (1987).
Tierno, et al., Biochem. 29:5948 (1990).
Jaffer, H. H.; Orchin, M., Theory and Applications of Ultraviolet Spectroscopy; John Wiley & Sons, Inc.: New York, 1962; pp. 337-341.
Foster et al., "Activation of Chlamydonas Rhodospin in Viro Does Not Require Isomerization of Retinal". Biochemistry 28:819-824, esp. p. 821 (1989).
Nakanishi et al., "Theory of rhodopsin activation: probable charge redistribution of excited state chromophore." Pure & Applied Chemistry 61, No. 3:361-362 (1989).
Asato et al., "Azulenic Retinoids and the Corresponding Bacteriorhodopsin Analogues. Usually Red-Shifted Pigments." J. Am. Chem. Soc. 112:7398-7399 (1989).
Suciu et al., "RO, A, 83,134". Chem Abstract 102, No. 12:315, 100823 (1984).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Azulenic retinoid compounds, compositions and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Azulenic retinoid compounds, compositions and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azulenic retinoid compounds, compositions and methods will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1726564

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.