Azulene derivatives, processes of their synthesis and their uses

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heavy metal containing doai

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260503, 556177, C07F 506

Patent

active

045956944

ABSTRACT:
A new series of azulene derivatives are disclosed. These compounds are stable to light and heat and are useful as anti-ulcerative and anti-inflammatory agents. Such compounds can be synthesized by reacting 2H-cyclohepta(b) furan-2-one or its derivative substituted by a lower alkyl with a suitable enamine derived from a corresponding aldehyde or ketone, and then sulfonating the compound resulting from said reaction.

REFERENCES:
patent: 3974299 (1976-08-01), Crosby et al.
patent: 4224240 (1980-09-01), Kane et al.
patent: 4283347 (1981-08-01), Kane et al.
Chemical Abstracts 88 115068n (1976).
Chemical Abstracts 88 130698m (1976).

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