Azulene derivatives and salts thereof

Details Azulene derivatives and salts thereof Azulene derivatives and salts thereof

2007-01-30

2007-01-30

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S001110

Reexamination Certificate

active

10491618

ABSTRACT:
The present invention provides an azulene derivative and a salt thereof, wherein an azulene ring is bonded to a benzene ring directly or via a lower alkylene which may be substituted with a halogen atom and the benzene ring is directly bonded to the glucose residue, and it is usable as a Na+-glucose cotransporter inhibitor, especially for a therapeutic and/or preventive agent for diabetes such as insulin-dependent diabetes (type 1 diabetes) and insulin-independent diabetes (type 2 diabetes), as well as diabetes-related diseases such as insulin-resistant diseases and obesity.

REFERENCES:
patent: 6515117 (2003-02-01), Ellsworth et al.
patent: 2001/0041674 (2001-11-01), Tomiyama et al.
patent: WO 98/31697 (1998-07-01), None
patent: WO 01/27128 (2001-04-01), None
patent: WO 02/083066 (2002-10-01), None
patent: WO 03/099836 (2003-12-01), None

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