Azulene derivatives and pharmaceutical compositions containing t

Details Azulene derivatives and pharmaceutical compositions containing t Azulene derivatives and pharmaceutical compositions containing t

1988-03-10

1990-03-27

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

549305, 558 33, 560119, 562501, 568303, 568348, A61K 31215, C07C 6974

Patent

active

049121340

ABSTRACT:
Azulene derivatives of the following formula ##STR1## wherein R.sup.1 stands for an alkyl group of 1 to 3 carbon atoms, R.sup.2 stands for an alkyl group of 1 to 3 carbon atoms, and R.sup.3 is at the 5- or 6-position and stands for an alkyl group of 1 to 6 carbon atoms, an aryl group of 6 to 9 carbon atoms or an aralkyl group of 7 to 10 carbon atoms; have antihyperlipidemic activity. Many of the compounds are also novel per se.

REFERENCES:
43rd Annual Meeting of the Chemical Society of Japan, Mar. 1981, in Tokyo, Japan, Abstract II P889 with English translation.
The Tohoku Local Meeting of the Chemical Society of Japan in Fukushima, Japan, Oct. 2, 3, 1981, with English translation.

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