Aztreonam β polymorph with very low residual solvent...

Details Aztreonam β polymorph with very low residual solvent... Aztreonam β polymorph with very low residual solvent...

2004-05-17

2008-11-18

Berch, Mark L (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07452991

ABSTRACT:
The invention relates to the β polymorph of Aztreonam, which contains less than 2.5% by weight residual solvent and to a process of making said polymorph. In the process of the invention, a polymorph of Aztreonam is dissolved in an absolute C1-6alcohol in the presence of a base to form a solution, an acid is added to the solution, and the solution is stirred efficiently.

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