Azolyl-substituted phenoxy-aminopropanol derivatives

Details Azolyl-substituted phenoxy-aminopropanol derivatives Azolyl-substituted phenoxy-aminopropanol derivatives

1983-03-14

1986-03-18

Rollins, Alton D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548262, C07D24904, C07D24908

Patent

active

045770301

ABSTRACT:
Phenoxy-aminopropanol derivatives of the formula ##STR1## wherein R is lower alkyl, X is oxygen or sulfur, n is the integer zero or 1, Y is methylene, ethylene or propylene or, when n is zero, Y can also be a group of the formula ##STR2## wherein the double-bond is trans and the carbon atom marked with an asterisk is linked to Z, and Z is a 5-membered aromatic heterocyclic ring which contains one or more nitrogen atoms as the sole hetero atom (s), said heterocyclic ring is linked to Y via a nitrogen atom, and may be substituted by halogen, lower alkyl, lower alkoxy, aryl, cyano or carboxamido, or on adjacent carbon atoms by a group of the formula

REFERENCES:
patent: 4006243 (1977-02-01), Strehlke et al.
patent: 4275071 (1981-06-01), Nardi et al.
patent: 4285961 (1981-08-01), Prucher et al.

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