Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-02-20
1998-04-07
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514254, 544368, 544369, A61K 31495, C07D41314, C07D41714, C07D41914
Patent
active
057365458
ABSTRACT:
Compounds useful in the preparation of pharmaceutical preparations for the treatment of microbial infection where such compounds are of structural Formula I ##STR1## or pharmaceutically acceptable salts thereof wherein: R.sup.1 is --CHO, --COCH.sub.3, --COCHCl.sub.2, --COCHF.sub.2, --CO.sub.2 CH.sub.3, --SO.sub.2 CH.sub.3, or --COCH.sub.2 OH; X.sup.1 and X.sup.2 are independently H, F, or Cl; and Q is a five membered ting heterocycle (azolyl ring) of the general form: ##STR2## wherein A, B, and C are independently oxygen (O), nitrogen (N), sulfur (S) or Carbon (C). In all cases, the piperazine nitrogen atom is attached at the carbon atom of the carbon-nitrogen double bond.
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Barbachyn Michael Robert
Gadwood Robert C.
Smith Herman Walden
Toops Dana Scott
Vaillancourt Valerie Ann
Bernhardt Emily
Corneglio Donald L.
Pharmacia & Upjohn Company
Yang Lucy X.
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