Azolyl methyl phenyl derivatives having aromatase inhibitory act

Details Azolyl methyl phenyl derivatives having aromatase inhibitory act Azolyl methyl phenyl derivatives having aromatase inhibitory act

1995-05-26

1996-12-24

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514382, 548260, 5482672, 5482674, 5482678, 5482686, A61K 3141, C07D40312, C07D40310, C07D24718

Patent

active

055873928

ABSTRACT:
Compounds exerting excellent aromatase inhibitory activity in vivo and in vitro with higher specificity and greater safety are provided together with the salts thereof. Using the same, there are also provided, prophylactic agents and/or therapeutical agents of estrogen-dependent diseases, contraceptive agents for females, and aromatase inhibitory agents for use in the form of reagents for human or animals. The compounds are of the formula (I), wherein R.sup.2 is represented by the formula (II) or (III). ##STR1##

REFERENCES:
patent: 4617307 (1986-10-01), Browne
patent: 4755526 (1988-07-01), Hirsch et al.
patent: 4916144 (1990-04-01), Strehlke et al.
patent: 5021434 (1991-06-01), Strehlke et al.
English language abstract of EP-A-600315 (1994).
"Imidazole Antimycotics: Inhibitors of Steroid Aromatase" by J. Ian Mason et al, Biochemical Pharmacology, 34, 1087-1902, 1985.

Affiliated with

Also associated with

Rating

Azolyl methyl phenyl derivatives having aromatase inhibitory act does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Azolyl methyl phenyl derivatives having aromatase inhibitory act, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azolyl methyl phenyl derivatives having aromatase inhibitory act will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1178798