Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-05-05
1980-09-16
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544250, 544262, 544263, 544271, 544278, 544281, 548161, 548254, 548266, 548329, 548337, 542422, 542414, 424269, 424270, 424273B, 424273R, A61K 31505, C07D51304, C07D51314
Patent
active
042230314
ABSTRACT:
6-(1H-Tetrazol-5-yl)thiozolo[3,2-a]pyrimidin-5-ones, 3-(1H-tetrazol-5-yl)-4H-pyrimido[2,1-b]benzothiazol-4-ones, and the corresponding imidazo- and triazolo-pyrimidines, thiones, and imines are useful as antiallergy and antiasthmatic compounds by virtue of their inhibitory action on the immediate hypersensitivity reaction in mammals and relaxant action on the tracheal muscle. Intermediates in the synthesis of these substances from 2-aminoazoles and ethoxy-methylene malononitrile also have smooth muscle relaxant and immediate hypersensitivity reaction inhibitory activity.
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Covington Robert R.
Temple, Jr. Davis L.
Yevich Joseph P.
Carnahan R. E.
Daus Donald G.
Mead Johnson & Company
Rivers Diana G.
Uloth R. H.
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