Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1999-09-01
2000-12-05
Celsa, Bennett
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514 17, 514822, A61K 3803, A61K 3804, A61K 3807, A61K 3808
Patent
active
061567329
ABSTRACT:
Azole derivatives of formula (I): ##STR1## are disclosed as useful in treating platelet-mediated thrombotic disorders.
REFERENCES:
Ervin, P.R. et al, (1995) Proceedings of the American Association for Cancer Research, Annual Meeting, 36:627, Abstract #3731, "The Active Species of Mammastatin as Expressed in Normal Mammary Cells but not in Mammary Carcinomas".
Ervin, P.R., (Mar. 1996) Proceedings of the American Association for Cancer Research Annual Meeting, 37:399, Abstract #2722, "Expression and Testing of Recombinant Mammastatin".
Ervin, P.R. et al., (1993) Proceeding of the American Association for Cancer Research, Annual Meeting, 34:150, Abstract #893, "Phosphoralation of the Growth Inhibitor Mammastatin in Normal but not Transformed Human Mammary Cells".
Ervin, P.R. et al., (Jun. 30, 1989) Science, 244:1585-1587 "Production of Mammastatin, a Tissue Specific Growth Inhibitor by Normal Human Mammary Cells".
Ervin, P.R., (1995) PHD Thesis from the University of Michigan, pp. 1-131 "Further Characterization and Cloning of the Growth Inhibitor Mammastatin".
Freemont et al., (Jan. 1984) Archives of Biochemistry and Biophysics, 228(1):342-352 "Human Skeletal--Muscle Aldolase: N-Terminal Sequence Analysis of CNBr--and o--lodosobenzoic Acid--Cleavage Fragments".
Garner I., (1994) Methods of Molecular Biology, 28:41-47 "Isolation of Total and Poly A+ RNA from Animal Cells".
Jerala, (1992) Biotechniques, 13:564 "Simultaneous Synthesis of Degenerate Oligo--nucleotides of Variable Length".
Kroczek, R.A., (1993) Journal of Chromatography, 618:133-145 "Review: Southern and Northern analysis".
Lasken, R.S. et al., (1985) Proceedings of the National Academy of Science U.S.A., 82(5):1301-1305 "A fidelity assay using "dideoxy" DNA sequencing: A measurement of sequence dependence and frequency of forming 5-bromouracil guanine base mispairs".
Nakayama, K. et al., (Jun. 1988) Bio/Technology, 6:693-697 "Construction of an ASD+ Expression--Cloning Vector: Stable Maintenance and High Level Expression of Cloned Genes in a Salmonella Vaccine Strain".
Nguyen, B. et al., (1995) Critical Reviews and Oncology/Hematology, 20:223-236 "The Biology of Growth Regulation in Normal and Malignant Breast Epithelium: From Bench to Clinic".
Short, J.M. et al., (Aug. 11, 1988) Nucleic Acids Research, 16(15):7583-7601 ".lambda. ZAP: a bacteriophage .lambda. expression vector with in vivo excision properties".
Soule, et al., (Jan. 1986) In Vitro Cellular & Developmental Biology, 22(1):6-12 "A Simplified Method For Passage and Long--Term Growth of Human Mammary Epithelial Cells".
Stuckey, J.A. et al., (Aug. 18, 1994) Nature, 370:571-575 "Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 .ANG. and the complex with tungstate".
Towbin H. et al., (1989) Journal of Clinical Chemistry, Clinical Biochemistry, 27(8):495-501 "Immumoblotting in the Clinical Laboratory".
Ullah et al., (Aug. 30, 1994) Biocheical and Biophysical Research Communications, 203(1):182-189 "The Complete Primary Structure Elucidation of Aspergillus ficuum (NIGER), pH 6.0, Optimum Acid Phosphatase".
Hoekstra William
Hulshizer Becky L.
Celsa Bennett
Ortho-McNeil Pharmaceuticals, Inc.
Palo Ralph R.
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