Azole derivatives antimycotic agents which release the active co

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31415

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active

045857822

ABSTRACT:
The invention relates to antimycotic compositions comprising (1) an antimycotic effective amount of an azole derivative having antimycotic activity, said azole derivative being in the form of particles less than 4.mu. in size, (2) an acid and/or a buffer system consisting of an organic acid and a salt thereof to provide a pH of 3 to 4 or less in aqueous solution and (3) an inert pharmaceutical carrier. Also included in the invention are methods for the short term treatment of vaginal infections utilizing the compositions of the invention.

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Burman; Principles of General Chemistry; 2/1969; pp. 207-209.

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