Azole derivatives and antifungal drugs containing the same as an

Details Azole derivatives and antifungal drugs containing the same as an Azole derivatives and antifungal drugs containing the same as an

1990-11-07

1992-05-05

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

548341, A61K 31415, C07D23360

Patent

active

051108267

ABSTRACT:
An azole derivative represented by the following formula (I): ##STR1## wherein X is a nitrogen atom or CH, Y is an oxygen atom, a sulfur atom, an imino group, a methylimino group or a group represented by .dbd.N O--, Z is one or two halogen atoms, in stands for a number of 1 to 2, the wavy line means that stereochemistry of the double bond is either E or Z; or an acid adduct thereof.
They exhibit strong antifungal activities and are very useful in the therapy for fungus diseases.
Also disclosed is an antifungal drug containing said compound as an active ingredient.

REFERENCES:
patent: 4055652 (1977-10-01), Walker

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