Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-02-03
1993-02-02
Morris, Patricia L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5482672, 5482674, 5482678, A01N 43653, C07D24908
Patent
active
051838249
ABSTRACT:
An azole derivative represented by the following formula (I): ##STR1## wherein X is a nitrogen atom or CH, Y is an oxygen atom, a sulfur atom, an imino group, a methylimino group or a group represented by .dbd.N.about.O--, Z is one or two halogen atoms, n stands for a number of 1 or 2, the wavy line means that stereochemistry of the double bond is either E or Z; or an acid adduct thereof.
They exhibit strong antifungal activities and are very useful in the therapy for fungus diseases.
Also disclosed is an antifungal drug containing said compound as an active ingredient.
REFERENCES:
patent: 5051439 (1991-09-01), Schermanz et al.
Hori Kimihiko
Ishida Koichi
Nomura Tomoko
Sakaguchi Akira
Suzuki Keiko
Kao Corporation
Morris Patricia L.
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