Azlactone activated polyalkylene oxides

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...

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525406, 525408, 526260, 548146, 548187, 548204, 548227, 548228, 528327, 528354, 514 2, 514 4, 5147721, 5147723, 514773, 514785, C08F28306, C08G 6532

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active

053210956

ABSTRACT:
Water-soluble azlactone activated polyalkylene oxides having improved hydrolytic stability and conjugates of the azlactone activated polyalkylene oxides with biologically active nucleophiles are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with biologically active nucleophiles are also disclosed.

REFERENCES:
patent: 4485236 (1984-11-01), Rasmussen et al.
patent: 5081197 (1992-01-01), Heilmann et al.
patent: 5157108 (1992-10-01), Krepski et al.
Carter, Organic Reactions, vol. III (Adams, ed., John Wiley & Sons, New York 1946), pp. 198-239.
Jones et al., J. Chem. Soc., (Perkin I), 3203-6 (1979).

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