Azithromycin monohydrate isopropanol clathrate and methods...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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C536S007400, C536S018500

Reissue Patent

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RE039087

ABSTRACT:
A novel form of azithromycin and processes for preparation of pure azithromycin monohydrate isopropanol clathrate (3 molecules of isopropanol for every 10 molecules of azithromycin monohydrate) has been obtained. Preparation of the novel form of azithromycin comprises the steps of dissolving azithromycin in isopropanol, followed by the slow addition of water to the organic solution.

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Federal Register, vol. 62, No. 247, 67381, Dec. 25, 1997.
International Search Report for Published Application No. WO 02/094843 A1, Application No. PCT/IB 02/01570; pp. 1-6.

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