Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1987-10-26
1990-05-15
Howard, Jacqueline V.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
A61K 3133
Patent
active
049258354
ABSTRACT:
This invention relates to methods of inhibiting the proliferation of prostate cancer cells comprising contacting the cells with an effective amount of a cytotoxic polyamine compound.
The invention also relates to methods of inhibiting the proliferation of prostate cancer cells in a subject afflicted with prostate cancer.
The invention further concerns therapeutic compositions comprising an effective prostate cancer cell proliferation inhibiting amount of 1-(4-aminobutyl) aziridine and a pharmaceutically acceptable carrier.
The invention also concerns two-component therapeutic compositions.
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patent: 4370323 (1983-01-01), Kampe et al.
patent: 4517183 (1985-05-01), Bosies et al.
patent: 4686215 (1987-08-01), Kalvinsh et al.
patent: 4704384 (1987-11-01), Driscoll et al.
Chemical Abstracts, 74:77493y, (1971).
Chemical Abstracts, vol. 74, p. 196F, (1971).
Howard Jacqueline V.
Medley Margaret B.
Sloan-Kettering Institute for Cancer Research
White John P.
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