Aziridino derivatives of nitroimidazoles and pharmaceutical comp

Details Aziridino derivatives of nitroimidazoles and pharmaceutical comp Aziridino derivatives of nitroimidazoles and pharmaceutical comp

1990-06-04

1991-07-30

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548339, C07D23391

Patent

active

050360965

ABSTRACT:
The present invention is novel aziridino derivatives of nitroimidazoles and pharmaceutical compositions of selected derivatives useful as radiosensitizing or chemosensitizing agents in the treatment of hypoxic tumor cells. Also, the present invention is a novel process for preparing both known and novel aziridino derivatives of nitroimidazoles having novel intermediates.

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