Aziridine compounds and methods of making and using them

Details Aziridine compounds and methods of making and using them Aziridine compounds and methods of making and using them

2005-04-05

2005-04-05

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S046000, C536S025340, C536S025300, C536S023100, C536S022100, C536S025310, C536S026100, C536S026300, C536S026130, C435S006120, C435S007100, C435S007400, C435S007720, C435S007720, C534S558000, C534S560000, C534S639000

Reexamination Certificate

active

06875750

ABSTRACT:
Aziridine derivatives of formula (I)are disclosed which can be used as cofactor for S-adenosyl-L-methionine-dependent methyltransferases.

REFERENCES:
Djordjevic and Stock, “Crystal structure of the chemotaxis receptor methyltransferase CheR suggests a conserved structural motif for binding S-Adenosylmethionine,”Structure5, 545-558, 1997.
Gong, W. et al. “Structure of Pvull DNA-(cytosine N4) methyltransferase, an example of domain permutation and protein fold assignment,”Nucleic Acids Research25 (14), 2702-2715, 1997.
Kagan and Clarke, “Widespread occurrence of three sequence motifs in diverse S-Adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes,”Archives of Biochemistry and Biophysics310 (2), 417-427, 1994.
Pignot, M., et al., “Coupling of a Nucleoside with DNA by a Methyltransferase,” Angew. Chem., Int. Ed., vol. 37, No. 20, pp. 2888-2891 (1998).

Affiliated with

Also associated with

Rating

Aziridine compounds and methods of making and using them does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aziridine compounds and methods of making and using them, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aziridine compounds and methods of making and using them will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3432096