Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-09-16
1978-08-29
Siegel, A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424275, C07D33324, A01N 900
Patent
active
041103424
ABSTRACT:
Azidomethylarylacetic acids and derivatives thereof are prepared by oxidative rearrangement of the corresponding azidomethylarylmethyl ketones effected by thallium (III) nitrate in the presence of methanol or ethanol and certain acids to obtain methyl or ethyl esters of the desired azidomethylarylacetate. When desired, the acids are obtained by hydrolysis of said esters. The azidomethylarylacetic acids are valuable intermediates in the preparation of aminomethylarylmethylpenicillins and aminomethylarylmethylcephalosporins.
REFERENCES:
chem. Abstracts, vol. 63, p. 9932a.
Pfizer Inc.
Siegel A.
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