Azidomethylarylacetic acids and esters thereof

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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424275, C07D33324, A01N 900

Patent

active

041103424

ABSTRACT:
Azidomethylarylacetic acids and derivatives thereof are prepared by oxidative rearrangement of the corresponding azidomethylarylmethyl ketones effected by thallium (III) nitrate in the presence of methanol or ethanol and certain acids to obtain methyl or ethyl esters of the desired azidomethylarylacetate. When desired, the acids are obtained by hydrolysis of said esters. The azidomethylarylacetic acids are valuable intermediates in the preparation of aminomethylarylmethylpenicillins and aminomethylarylmethylcephalosporins.

REFERENCES:
chem. Abstracts, vol. 63, p. 9932a.

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