Azido-substituted octopamine agonists and the use thereof to con

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142288, 514275, 514329, 514370, 514377, 514392, 514426, 544 53, 544 54, 544 88, 544330, 544332, 546223, 548190, 548193, 548194, 548198, 548234, 548315, 548559, A01N 4386, A01N 4350, C07D23350

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active

048928712

ABSTRACT:
The invention is directed to azido-substituted octopamine agonists and the radiolabeled derivatives thereof. The invention also relates to past controlling compositions comprising the azido-substituted octopamine agonists of the invention.
The invention also relates to methods of controlling invertebrate pests by bringing the pest into contact with an invertebrate pest-controlling composition of the invention and to an apparatus for controlling invertebrate pests utilizing the pest-controlling compositions of the invention. The pest-controlling compositions may be used alone or in conjunction with ultraviolet light.
The invention also relates to methods for the isolation of octopamine receptor proteins utilizing the radiolabeled azido-substituted octopamine agonists of the invention.

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Chemical Abstracts, 104:289182 (1986) [Kawamara, R., et al., Eur. J. Pharmacol., 1985, 117(1), 43-50].
Nathanson, J. A., Mol. Pharm. 28: 254-268 (1985).
Nathanson, J. A., Proc. natl. Acad. Sci. (U.S.A.) 82: 599-603 (1985).
Hollingworth, R. M., Environ. Health Persp. 14: 57-69 (1976).
De Jong, A. P. et al., Eur. J. Pharm. 69: 175-188 (1981).
Matsumura, F. et al., Environ. Health Persp. 14: 71-82 (1976).

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