Azetitin-2-ores and process for preparing same

Details Azetitin-2-ores and process for preparing same Azetitin-2-ores and process for preparing same

1972-09-12

1976-04-27

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602391, 260243C, 260949, C07D20508

Patent

active

039534243

ABSTRACT:
Novel azetidin-2-ones having in the 4-position an S-attached saturated or unsaturated, substituted or unsubstituted aliphatic group having at least 2 carbon atoms and in the 3-position an amino or blocked amino group are provided. The novel compounds are useful as intermediates in the production of cephalosporins, penicillins and related .beta.-lactam antibiotic compounds. The novel compounds are prepared by cleaving a penicillin-1-oxide in the presence of a compound containing a nucleophilic carbon-carbon multiple bond not forming part of a ring.

REFERENCES:
patent: 3755342 (1973-08-01), Heusler et al.

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