Azetidinone intermediates for the preparation of penem derivativ

Details Azetidinone intermediates for the preparation of penem derivativ Azetidinone intermediates for the preparation of penem derivativ

1986-04-04

1988-02-16

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540360, C07D20508, C07D40112, C07D40114, C07D40312

Patent

active

047256788

ABSTRACT:
Certain 2-substituted-2-penem-3-carboxylic acid compounds and pharmaceutically-acceptable salts thereof can be prepared from the appropriate xanthate or trithiocarbonate by desulfurization and addition of an electrophilic sulfur compound followed by halogenation and ring closure. The corresponding desulfurized and halogenated olefinic intermediates are disclosed.

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