Azetidinone derivatives

Details Azetidinone derivatives Azetidinone derivatives

1977-09-08

1980-10-14

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602453, 2603458R, 544 60, 544111, 546133, 546208, 546275, C07D20508, C07D40512, C07D41304, C07D41704

Patent

active

042280745

ABSTRACT:
.beta.-Lactam compounds of the formula (I) ##STR1## (wherein R represents an esterified carboxyl group, --NR.sup.1 R.sup.2 R.sup.3 represents the residue of a nitrogen base, and R.sup.4 represents a hydrogen atom, a hydroxyl group or acylated or etherified hydroxyl group or the residue of a sulphur nucleophile) are disclosed, together with processes for their preparation. The compounds are valuable intermediates for the preparation or purification of further .beta.-lactam compounds having .beta.-lactamase inhibitory activity.

REFERENCES:
patent: 4018782 (1977-04-01), Wolfe
Nobats et al., Basic Principles of Organic Chemistry (1964), p. 484.

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