Azetidine derivatives and hypotensive compositions thereof

Details Azetidine derivatives and hypotensive compositions thereof Azetidine derivatives and hypotensive compositions thereof

1991-09-09

1992-11-17

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

548950, A61K 31395, C07D20314

Patent

active

051643855

ABSTRACT:
Azetidine derivatives of formula ##STR1## and their pharmaceutically acceptable acid addition salts are disclosed. In the formula R is hydrogen or one or more specified substituents. The compounds have hypotensive activity. Some are also 5-HT.sub.1A agonists.

REFERENCES:
patent: 5026857 (1991-06-01), Schohe et al.
patent: 5053430 (1991-10-01), Grauert et al.
patent: 5075303 (1991-12-01), Cliffe

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