Azetidine compounds and process for production

Details Azetidine compounds and process for production Azetidine compounds and process for production

1978-03-23

1979-08-07

Randolph, John D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260239A, C07D40102

Patent

active

041638565

ABSTRACT:
Novel azetidine, and particularly 3-pyridyl-azetidine, compounds are disclosed. These compounds are produced from .gamma.-amino alcohols by a sequence comprising disulfonation to produce the sulfonamido-alkylsulfonate and then cyclization to the N-sulfonylazetidine. These azetidine compounds may then be transformed, as desired, to various N-derivatives by substitution of hydrogen or other univalent organic groups on the secondary amine of the azetidine ring.

REFERENCES:
testa et al., Chem. Abstracts, vol. 57, col. 15039 (1962).
Secor et al., Chem. Abstracts, vol. 86, abst. 120778g (1977).
Chem. Abstracts, Subject Index, vol. 86, p. 4535CS (1977).
Klingsberg, Pyridine and Its Derivatives, Part One, pp. 2-3, Interscience Publishers, NY (1960).

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