Azetidine compounds and process for production

Details Azetidine compounds and process for production Azetidine compounds and process for production

1978-03-23

1979-08-07

Randolph, John D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260239A, C07D40102

Patent

active

041638557

ABSTRACT:
Novel azetidine, and particularly 2-pyridyl-azetidine, compounds are disclosed. These compounds are produced from amino-esters by a sequence comprising conversion to the sulfonamide, reduction of the ester to the alcohol, sulfonation of the resultant alcohol and cylization to the N-sulfonylazetidine. This azetidine compound may then be transformed, as desired, to various N-derivatives by substitution of hydrogen or other univalent organic groups on the secondary amine of the azetidine ring.

REFERENCES:
testa et al, Chem. Abstracts vol. 57, col. 15039 (1962).
Secor et al, Chem. Abstracts, vol. 86, abst. 120778g (1977).
Chem. Abstracts Subject Index. vol. 86, p. 4535Cs (1977).
Klingsberg, Pyridine and Its Derivatives, Part One, pp. 2-3, Interscience Publishers, Inc. NY (1960).

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