Azepine indanyl and tetralin butyrophenones

Details Azepine indanyl and tetralin butyrophenones Azepine indanyl and tetralin butyrophenones

1974-09-06

1976-04-27

Rush, Raymond V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602393T, 26029362, 26032681, 2603405, 2603409, 260473F, 260566A, 260 61BF, 260590R, 424244, 424274, 424256, 260566AE, 260590FA, C07D22332, C07D22314

Patent

active

039534251

ABSTRACT:
Novel azepine spiro indans, azepine spiro tetralins, pharmacologically acceptable acid addition salts thereof and processes for their production. The compounds of this invention and the pharmacologically acceptable acid addition salts thereof have central nervous system activity, they are especially useful as central nervous system depressants.

REFERENCES:
Tokura et al., Bull. Chem. Soc. Japan, 37, 138 (1964).
Roberts et al., Basic Princ. of Org. Chem. 1964, pp. 659, 661.
Nice et al., J. Med. Chem. 9, 765 (1966).
Rice et al., J. Med. Chem. Vol. 6, 388 (1963).
Grogan et al., J. Med. Chem. Vol. 8, 62, (1965).

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