Azepanes and their ring homologues having protein kinase inhibit

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546194, 546207, 546208, 544360, 544359, C07D40112

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active

059144068

ABSTRACT:
The compounds of formula I: wherein R.sup.1 --R.sup.9, R.sup.15, A, X, Y, and Z have the meaning given in the specification are active as protein kinase inhibitors and can be used as medicaments, particularly for the treatment of inflammatory skin disorders and alopecia.

REFERENCES:
patent: 5583222 (1996-12-01), Barbier et al.
patent: 5750706 (1998-05-01), Barbier et al.

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