Azepanes and their ring homologues having protein kinase inhibit

Details Azepanes and their ring homologues having protein kinase inhibit Azepanes and their ring homologues having protein kinase inhibit

1995-01-04

1996-12-10

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

540597, 540598, 540599, 540602, 540604, 540603, C07D40106, C07D40306, C07D41306, C07D22312

Patent

active

055832229

ABSTRACT:
The compounds of formula I ##STR1## wherein R.sup.1 -R.sup.9, R.sup.15, A, X, Y, Z and n have the meaning given in the specification are active as protein kinase inhibitors and can be used as medicaments, particularly for the treatment of inflammatory skin disorders and alopecia.

REFERENCES:
Muller, et al, Synthesis of (3R,4R)-3-Amino-hydroxy-hexahydorazepine, the Chiral Constituent of the Antibiotic Ophiocordin, Leibigs Ann. Chem 651-655 (1993) publication month not provided.
Koenig, et al. Konsitution von Ophiocordin, einem Antibiotikum mit antifungischen Eigenschaften, Chem. Ber. 112, 2221-2226 (1980) publication month not provided.
Kulanthaivel, et al, J. Am. Chem. Soc. vol. 115, pp. 6452-6453 (1993) Month of publication not provided.

Affiliated with

Also associated with

Rating

Azepanes and their ring homologues having protein kinase inhibit does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Azepanes and their ring homologues having protein kinase inhibit, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Azepanes and their ring homologues having protein kinase inhibit will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-424957