Azepane derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S217040, C514S217050, C514S217060, C514S217070, C514S217080, C514S217090, C514S217100, C514S217110, C540S596000, C540S597000, C540S598000, C540S599000, C540S600000, C540S601000, C540S602000, C540S603000, C540S604000, C540S605000, C540S606000, C540S607000, C540S608000

Reexamination Certificate

active

06887864

ABSTRACT:
This invention provides novel azepane derivatives or pharmaceutically acceptable salts thereof, according to the general formula (I)wherein the symbols are defined in the specification, as well as processes for their manufacture. The compounds according to this invention possess anti-cell proliferation activity and show an increased plasma-stability.

REFERENCES:
patent: 296 110 (1988-12-01), None
patent: 657 458 (1995-06-01), None
patent: 663 393 (1995-07-01), None
patent: 802 190 (1997-10-01), None
patent: 1 020 471 (2000-07-01), None
patent: WO 9420062 (1994-09-01), None
patent: WO 9530640 (1995-11-01), None
patent: WO 9702249 (1997-01-01), None
David Tanner, et al., Tetrahedron, vol. 53, No. 13, pp. 4857-4868 (1997).
G. Erik Jagdmann, Jr., et al., Bioorganic & Medicinal Chemistry Letters, vol. 5, No. 17, pp. 2015-2020 (1995).

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